Addiction, Health, Behaviour Change | CGL

Research projects

We have a strong focus on safety and quality improvement. This is evident in our research and development programme.
We have been involved with over 20 research projects over the last year and a half, looking at everything from: ‘The neural basis of gambling cognitions’ to ‘Destitution in the UK’.

We are currently working with 28 universities, maintaining regular contact with consultants, readers, professors and students that are completing research studies. We are keen to contribute to the wider academic community so we encourage students to conduct their research with us whenever possible and appropriate. Our involvement with students ranges from undergraduate dissertations to PhD theses, from institutions across the United Kingdom.
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Recent projects

TIPS™ - Evaluation of non-invasive drug screening from fingertip sweat to support drug rehabilitation treatment programs

Change Grow Live has piloted the world’s first portable fingerprint-based drug screening system as part of its support and rehabilitation initiatives for service users and families affected by drug misuse. The non-invasive drug screening system from Intelligent Fingerprinting is easy to use, and will enable CGL to determine in minutes if a client has recently used any of the four drugs in the test – amphetamines, cannabis, cocaine and opiates. The Intelligent Fingerprinting solution detects drug use by analysing chemicals, known as metabolites, contained in the minute traces of sweat found in a fingerprint sample.

Volunteers have been recruited into the study and be asked to provide fingertip sweat samples along with an oral fluid sample. The fingertip samples were analysed by Intelligent Fingerprinting whilst the oral fluid samples were sent to an accredited third party laboratory for screening and confirmation.

Researcher: Dr Paul Yates

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Change Grow Live has piloted the world’s first portable fingerprint-based drug screening system
Dr Tim Millar - Reader at the University of Manchester
"Working with CGL maximises the impact of my research and the potential to change people’s lives."

Hepatitis C Awareness Through to Treatment (HepCATT)

Change Grow Live service users in Walsall have been involved in this study, funded to assess the impact of a complex intervention in Specialist Drugs Services aimed at increasing the numbers of hepatitis C virus (HCV)-infected people who inject drugs (PWID) engaging with HCV therapy. This was done through placing a half-time facilitator within 3 intervention Specialist Drug Services clinics (of which Walsall was one) with the brief “test the untested PWID” for evidence of HCV infection, and “refer the known positives”.

The study has now concluded and the researchers are currently seeking publication. The data strongly suggest that investment of resources into SDS clinics can have a dramatic impact on the numbers of HCV infections diagnosed and the numbers of patients engaging with therapy.

The study has now concluded and the researchers are currently seeking publication.

Researchers: William Irving et al.

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A three-arm, Randomised Controlled Trial of the effectiveness and cost-effectiveness of adjunctive medication management and contingency management to enhance adherence to medications for relapse prevention in alcohol dependence (ADAM).

Change Grow Live is working with academics and clinical experts from across the country to support this important study into the treatment of alcohol dependence. Providing effective treatment, including the prescribing of acamprosate (Campral), helps those who have, problems with alcohol reduce the risk of drinking again. A team of researchers led by Professor Colin Drummond, King's College London, have designed interventions delivered by pharmacists via a central telephone service to help support people to take acamprosate as it is prescribed. The ADAM study is a randomised controlled trial to determine the efficacy of medication management with and without contingency management to increase adherence to acamprosate compared to treatment as usual.

A number of Change Grow Live services in Birmingham, Hull, London, Rotherham and Scunthorpe are offering people undergoing treatment for alcohol problems the opportunity to participate in this groundbreaking research. With their agreement, those suitable to participate in the study will be put in contact with the research team.

Researchers: Colin Drummond, et al.

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KARE: A phase II, randomised, double-blind, placebo-controlled, multi-site, parallel group clinical trial to examine ketamine as a pharmacological treatment for alcohol dependence in an alcohol dependent population

Change Grow Live is involved in a study that is looking to reduce the risk of relapse in people with alcohol problems who are trying to stay sober using a combination of ketamine and cognitive behavioural therapy. The study involves participants taking part in 7 psychological therapy sessions while also receive a ketamine of placebo infusion. The study aims to show the value of Ketamine in helping with alcohol addiction. It is taking place in London services.

Researchers: Celia Morgan and Will Lawn

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The problem of drug related litter (discarded needles and syringes) in Manchester

Change Grow Live is involved in a research project funded by Manchester City Council’s Population Health and Wellbeing Team. The research aims to gain a clear understanding of the nature and prevalence of drug-related litter (DRL), such as discarded needles and syringes, in Manchester. It will focus on: reviewing existing service provision, establishing the scale of DRL in the city, identifying any ‘hot spots’ for DRL, investigating what the reasons behind the problem might be and providing recommendations to the Council and service providers as to how incidents of DRL can be best addressed.
Researcher: Paul Gray
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